Stability of natural polyphenol fisetin in eye drops Stability of fisetin in eye drops

Stability of cefazolin sodium eye drops.

OBJECTIVE Assessing the stability of cefazolin sodium in preservative-free and preservative-containing eye drops. METHOD Extemporaneous formulations of eye drops were prepared from a commercially-available parenteral product of cefazolin sodium: eye drops 'A' contained 50mg/ml of cefazolin sodium in 0.45% w/v sodium chloride solution, and eye drops 'B' contained 50 mg/ml, 0.005% w/v thiomersa...

Stability of sulphacetamide eye drops at higher temperature.

Suiphacetamide solutions at higher temperature degrade to its hydrolysed product, sulphanilamide, with a first-order rate constant. The degraded products are identified and characterised by chromatography and spectrophotometry. Attempts are made for the evaluation of kinetics, entropy and enthal changes activation energy and frequency factors during heating of sulphacetamide solutions. The dete...

Eye-drops in Tonometry.

Prescription of eye drops.

The aim of this study was to assess whether patients have their ocular drops correctly prescribed during non-ophthalmic admissions to hospital. A retrospective review of notes of patients who were admitted to hospital for general medical or surgical care, while on regular eye drops at the time of admission was performed. Twenty two patients were on regular ocular medication when admitted. Only ...

Development and Validation of a Rapid Derivative Spectrophotometric Method for Determination of Tropicamide in Eye Drops

      Tropicamide is an antimuscarinic agent used as eye drops for refractive examinations. The aim of this study was to develop a simple and suitable analytical method for determination of tropicamide in eye drops in the presence of excipients. A zero-crossing third and fourth derivative spectrophotometric method was described for determination of tropicamide in eye drops. The measurements wer...